International consensus statement on an update of the classification criteria




















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Evaluation Evaluation of profound sinus bradycardia should include assessing the chronotropic response to mild aerobic activity, such as running on the spot or climbing stairs. Profound first-degree heart block Mild to moderate first-degree heart block with a PR interval of to ms may be present in athletes due to increased vagal tone. Evaluation A small amount of aerobic activity should be performed to assess if the PR interval shortens appropriately. Considerations in high-dynamic athletes In high-level endurance athletes, such as cyclists, triathlon athletes and rowers, concern has been raised about the high volume and pressure loads on the right ventricle that could promote or induce ARVC.

Figure 20 ECG from a patient with arrhythmogenic right ventricular cardiomyopathy. Ventricular arrhythmias Ventricular couplets, triplets and non-sustained ventricular tachycardia always require investigation. Evaluation If ventricular arrhythmias are seen, the evaluation should include a thorough family history, an echocardiogram to evaluate for structural heart disease, cardiac MRI to assess for ARVC or other cardiomyopathies, ambulatory ECG monitor and exercise ECG test.

Temporary restriction during secondary evaluation of ECG abnormalities Temporary restriction from athletic activity should be considered for athletes with abnormal ECGs of uncertain clinical significance until secondary investigations are completed. Psychological considerations of caring for the athlete with potentially lethal cardiac disease Athletes diagnosed with serious cardiac diseases, regardless of the method used for disease detection, are at risk for psychological morbidity and represent an emotionally vulnerable population.

Conclusion Accurate ECG interpretation in athletes requires adequate training and an attention to detail to distinguish physiological ECG findings from abnormal ECG findings that might indicate the presence of cardiac pathology. Incidence of sudden cardiac death in national collegiate athletic association Athletes. Circulation ; : — Sudden deaths in young competitive Athletes: analysis of deaths in the United States, Incidence, etiology, and comparative frequency of sudden cardiac death in NCAA Athletes: a decade in review.

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Br J Sports Med ; 46 Suppl 1 : i6 — 8. Feasibility and findings of large-scale electrocardiographic screening in young adults: data from 32, subjects.

Heart Rhythm ; 8 : — 9. Electrocardiographic interpretation in Athletes: the 'Seattle criteria'. Br J Sports Med ; 47 : — 4. Cardiovascular pre-participation screening of young competitive Athletes for prevention of sudden death: proposal for a common european protocol. Eur Heart J ; 26 : — Prevalence of abnormal electrocardiograms in a large, unselected population undergoing pre-participation cardiovascular screening. Eur Heart J ; 28 : — Trends in sudden cardiovascular death in young competitive Athletes after implementation of a preparticipation screening program.

Jama ; : — Br J Sports Med ; 46 : — Normal electrocardiographic findings: recognising physiological adaptations in Athletes. Br J Sports Med ; 47 : — Abnormal electrocardiographic findings in Athletes: recognising changes suggestive of cardiomyopathy.

Abnormal electrocardiographic findings in Athletes: recognising changes suggestive of primary electrical disease. The Seattle criteria increase the specificity of preparticipation ECG screening among elite Athletes.

Br J Sports Med ; Electrocardiography-inclusive screening strategies for detection of cardiovascular abnormalities in high school Athletes. Heart Rhythm ; 11 : — 9. Comparison of three ECG criteria for athlete pre-participation screening.

J Electrocardiol ; 47 : — Clinical significance of electrocardiographic right ventricular hypertrophy in Athletes: comparison with arrhythmogenic right ventricular cardiomyopathy and pulmonary hypertension. Eur Heart J ; 34 : — Should Axis deviation or atrial enlargement be categorised as abnormal in young Athletes? Eur Heart J ; 34 : — 8. Comparison of electrocardiographic criteria for the detection of cardiac abnormalities in elite black and white Athletes.

Comparison of three current sets of electrocardiographic interpretation criteria for use in screening Athletes. Heart ; : — Standardised criteria improve accuracy of ECG interpretation in competitive Athletes: a randomised controlled trial. Br J Sports Med ; 48 : — Heart Rhythm ; 12 : — 6. Reliability and validity of clinician ECG interpretation for Athletes.

Ann Noninvasive Electrocardiol ; 19 : — Accuracy of interpretation of preparticipation screening electrocardiograms.

J Pediatr ; : — 8. Circulation ; : e — e J Cardiovasc Magn Reson ; 11 : 2. Clinical significance of abnormal electrocardiographic patterns in trained Athletes. Prevalence and significance of T-wave inversions in predominantly caucasian adolescent Athletes. Eur Heart J ; 30 : — Eur Heart J ; 32 : — ECG and morphologic adaptations in Arabic Athletes: are the European society of cardiology's recommendations for the interpretation of the lead ECG appropriate for this ethnicity?

Electrocardiographic changes in highly trained junior elite Athletes. Br J Sports Med ; 33 : — OpenUrl Abstract. The athletic heart syndrome. The standard electrocardiogram as a screening test for hypertrophic cardiomyopathy.

Am J Cardiol ; 76 : — Abstract ecg screening criteria for LVH does not correlate with diagnosis of hypertrophic cardiomyopathy. Circulation ; 12 : 51 9 0 0. Performance of the european society of cardiology criteria for ECG interpretation in Athletes.

Heart ; 97 : — 7. Prevalence and clinical meaning of isolated increase of QRS voltages in hypertrophic cardiomyopathy versus athlete's heart: relevance to athletic screening. Int J Cardiol ; : — 7. Electrocardiographic features of sarcomere mutation carriers with and without clinically overt hypertrophic cardiomyopathy. Am J Cardiol ; : — Significance of electrocardiographic right bundle branch block in trained Athletes. Am J Cardiol ; : — 9. Long-term outcome associated with early repolarization on electrocardiography.

N Engl J Med ; : — Sudden cardiac arrest associated with early repolarization. The early repolarization pattern: a consensus paper. J Am Coll Cardiol ; 66 : — 7. Early repolarization: electrocardiographic phenotypes associated with favorable long-term outcome. Early repolarization in an ambulatory clinical population.

Inferolateral early repolarization in Athletes. J Interv Card Electrophysiol ; 31 : 33 — 8. Early repolarization pattern in competitive Athletes: clinical correlates and the effects of exercise training. Circ Arrhythm Electrophysiol ; 4 : — The early repolarization pattern in the general population: clinical correlates and heritability. J Am Coll Cardiol ; 57 : — 9.

J-point elevation in survivors of primary ventricular fibrillation and matched control subjects: incidence and clinical significance. J Am Coll Cardiol ; 52 : — 8.

Early repolarization patterns associated with increased arrhythmic risk are common in young non-Caucasian Australian males and not influenced by athletic status. Heart Rhythm ; 12 : — Benign clinical significance of J-wave pattern early repolarization in highly trained Athletes.

Heart Rhythm ; 11 : — Cardiac adaptation to exercise in adolescent Athletes of African ethnicity: an emergent elite athletic population. The athlete's heart in adolescent Africans: an electrocardiographic and echocardiographic study. J Am Coll Cardiol ; 59 : — Ethnic differences in physiological cardiac adaptation to intense physical exercise in highly trained female Athletes. Prevalence of cardiomyopathy in Italian asymptomatic children with electrocardiographic T-wave inversion at Preparticipation screening.

Echocardiographic findings in peri-pubertal Athletes with or without inverted T waves at electrocardiogram. Intrinsic sinus and atrioventricular node electrophysiologic adaptations in endurance Athletes. J Am Coll Cardiol ; 39 : — 8. Electrocardiographic findings in male veteran endurance Athletes. Br Heart J ; 61 : — Wenckebach A-V block: a frequent feature following heavy physical training. Am Heart J ; 90 : — The athlete's heart. Heart ; 98 : — Comparison of frequency of significant electrocardiographic abnormalities in endurance versus nonendurance Athletes.

ECG findings in competitive rowers: normative data and the prevalence of abnormalities using contemporary screening recommendations. Br J Sports Med ; 49 : — 6.

Cardiovascular screening in adolescents and young adults: a prospective study comparing the Pre-participation physical evaluation monograph 4th edition and ECG. Br J Sports Med ; 48 : — 8. Cardiovascular screening with electrocardiography and echocardiography in collegiate Athletes. Cardiovascular screening in college Athletes with and without electrocardiography: a cross-sectional study. Ann Intern Med ; : — Significance of false negative electrocardiograms in Preparticipation screening of Athletes for hypertrophic cardiomyopathy.

The relationship between electrocardiographic changes and CMR features in asymptomatic or mildly symptomatic patients with hypertrophic cardiomyopathy. Int J Cardiovasc Imaging ; 30 Suppl 1 : 55 — Clinical profile of Athletes with hypertrophic cardiomyopathy.

Circ Cardiovasc Imaging ; 8 : e Systematic comparison of digital electrocardiograms from healthy Athletes and patients with hypertrophic cardiomyopathy. J Am Coll Cardiol ; 65 : — 3. Ventricular arrhythmias in the North American multidisciplinary study of ARVC: predictors, characteristics, and treatment. J Am Coll Cardiol ; 64 : — BMC Cardiovasc Disord ; 15 : 4.

Electrocardiographic findings of repolarization in athletic students and control subjects. Cardiology ; 84 : 51 — Prevalence of electrocardiographic abnormalities in West-Asian and African male Athletes. Br J Sports Med ; 46 : — 7. Prevalence of electrocardiographic anomalies in young individuals: relevance to a nationwide cardiac screening program. J Am Coll Cardiol ; 63 : — Outcomes in Athletes with marked ECG repolarization abnormalities.

Recognition and significance of pathological T-wave inversions in Athletes. Hypertrophic cardiomyopathy phenotype revisited after 50 years with cardiovascular magnetic resonance. J Am Coll Cardiol ; 54 : — 8. Eur Heart J ; 35 : — Electrocardiographic anterior T-wave inversion in Athletes of different ethnicities: differential diagnosis between athlete's heart and cardiomyopathy. Eur Heart J ; 37 : — Prevalence and significance of anterior T wave inversion in young white Athletes and non Athletes.

J Am Coll Cardiol ; 69 : 1 — 9. Relation of electrocardiographic abnormalities and patterns of left ventricular hypertrophy identified by 2-dimensional echocardiography in patients with hypertrophic cardiomyopathy.

Am J Cardiol ; 51 : — ST-segment depression as a risk factor in hypertrophic cardiomyopathy. Europace ; 11 : — 9. MacAlpin RN. Clinical significance of QS complexes in V1 and V2 without other electrocardiographic abnormality. Ann Noninvasive Electrocardiol ; 9 : 39 — Computerized Q wave dimensions in Athletes and hypertrophic cardiomyopathy patients.

J Electrocardiol ; 48 : — 7. The Seattle ECG criteria for abnormal Q waves is not associated with findings of cardiomyopathy on limited echocardiography. Electrocardiographic right and left bundle branch block patterns in Athletes: prevalence, pathology, and clinical significance. J Electrocardiol ; 48 : — 4. Addition of the electrocardiogram to the preparticipation examination of college Athletes.

Clin J Sport Med ; 20 : 98 — Intraventricular conduction delay in a standard lead electrocardiogram as a predictor of mortality in the general population. Prognostic significance of quantitative QRS duration. J Electrocardiol ; 48 : — 8. Relative effects of left ventricular mass and conduction disturbance on activation in patients with pathological left ventricular hypertrophy. Br Heart J ; 71 : — Heart Rhythm ; 13 : — Cardiovascular screening in college Athletes.

J Am Coll Cardiol ; 65 : — 5. Heart Rhythm ; 9 : — Failure of the exercise test to predict the anterograde refractory period of the accessory pathway in Wolff Parkinson white syndrome.

Pacing Clin Electrophysiol ; 11 : — 8. Intermittent preexcitation in the Wolff-Parkinson-White syndrome. Am J Cardiol ; 52 : — 6. Ventricular fibrillation in the Wolff-Parkinson-White syndrome. N Engl J Med ; : — 5. Prevalence of the congenital long-QT syndrome. Circulation ; : — 7. Cardiomyopathic and channelopathic causes of sudden unexplained death in infants and children.

Annu Rev Med ; 60 : 69 — Sudden death in young adults: an autopsy-based series of a population undergoing active surveillance. J Am Coll Cardiol ; 58 : — Incidence, causes, and survival trends from cardiovascular-related sudden cardiac arrest in children and young adults 0 to 35 years of age: a year review. Cardiological assessment of first-degree relatives in sudden arrhythmic death syndrome.

Lancet ; : — 9. Mayo Clin Proc ; 79 : — 4. Sudden unexplained death: heritability and diagnostic yield of cardiological and genetic examination in surviving relatives. Etiology of sudden death in sports: insights from a united kingdom regional registry. J Am Coll Cardiol ; 67 : — Inaccurate electrocardiographic interpretation of long QT: the majority of physicians cannot recognize a long QT when they see one.

Heart Rhythm ; 2 : — Accurate electrocardiographic assessment of the QT interval: teach the tangent. Heart Rhythm ; 5 : — 8. Bazett HC. An analysis of the time-relations of electrocardiograms. Heart : — Heart Rhythm ; 7 : — 9. Quantitative analysis of T wave abnormalities and their prognostic implications in the idiopathic long QT syndrome. Overview Fingerprint. Abstract New clinical, laboratory and experimental insights, since the publication of the Sapporo preliminary classification criteria for antiphospholipid syndrome APS , had been addressed at a workshop in Sydney, Australia, before the Eleventh International Congress on antiphospholipid antibodies.

Access to Document Link to publication in Scopus. Fingerprint Dive into the research topics of 'International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome APS '. Together they form a unique fingerprint. View full fingerprint. Journal of Thrombosis and Haemostasis , 4 2 , In: Journal of Thrombosis and Haemostasis , Vol.

Journal of Thrombosis and Haemostasis. Miyakis, S. In: Journal of Thrombosis and Haemostasis. Reber and Y. Shoenfeld and A. AU - Lockshin, M. AU - Atsumi, T.



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